CORDIS Project
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This project focuses on developing a new method for the asymmetric halogenation of olefins using intermolecular nucleophiles. By tuning the stability of halonium complexes, the project aims to enhance the efficiency of producing chiral compounds, which are crucial in pharmaceuticals and other chemical applications.
Chirality is fundamental to the vast majority of molecular recognition processes.
Therefore, asymmetric synthesis is a cornerstone in the efficient production of modern pharmaceuticals and many other chemicals.
Despite ongoing efforts, however, the asymmetric halogenation of olefins using intermolecular nucleophiles has not been achieved with useful enantiomeric excess ratios.
The development of a feasible approach has challenged the field to the day.
It is highly desirable for the tremendous ex…
UGOT - GOETEBORGS UNIVERSITET/UNIVERSITY OF GOTHENBURG
GOETEBORGS UNIVERSITET
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