CORDIS Project
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This project develops a novel imaging technique that combines optical projection tomography with geometric morphometrics to analyze gene expression in developing organs. It focuses on understanding congenital defects using a mouse model of Apert syndrome.
Development of new imaging techniques, such as optical projection tomography (OPT), to visualize gene expression patterns within developing structures in a 3D framework has revolutionized developmental biology research.
However, methods to precisely quantify these 3D expression distributions in a systematic manner are still lacking.
We are developing a novel approach to combine OPT with Geometric Morphometrics (GM) methods to quantify the relationship between morphology and gene expression shape…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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