CORDIS Project
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This project focuses on myelodysplastic syndromes (MDS), a group of blood disorders. It aims to understand the interactions between hematopoietic stem cells and their surrounding niche, with the goal of developing new therapeutic strategies for MDS patients.
Myelodysplastic syndromes (MDS) are heterogeneous clonal hematopoietic stem cell diseases mainly affecting the elderly (45/100,000 in >70 years).
The prevalence of MDS is expected to rise mainly as a result of an aging population. MDS is characterized by ineffective production of mature blood cells with peripheral cytopenias and the propensity to evolve to acute myeloid leukemia.
Most MDS patients rely on continuous blood transfusions resulting in significant costs to healthcare systems and, mos…
CHEMOTHERAPEUTISCHES FORSCHUNGSINSTITUT GEORG-SPEYER-HAUS STIFTUNG
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