CORDIS Project
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This project investigates liver diseases, particularly non-alcoholic fatty liver disease, using a novel 3D spheroid system to study chronic drug toxicity and liver function. The research aims to identify mechanisms and biomarkers for liver disease treatment and develop methods for hepatocyte regeneration for transplant…
The liver is a vital organ for synthesis and detoxification.
The most significant liver diseases are hepatitis, non alcoholic fatty liver disease (NAFLD), non-alcoholic fatty liver steatohepatitis (NASH), carcinoma and cirrhosis.
An additional and important cause of liver injury is adverse drug reactions (ADRs).
In particular NAFLD is the most common liver disease affecting between 20% and 44% of European adults and 43-70% of patients with type 2 diabetes, and is one prime cause for chronic an…
KAROLINSKA INSTITUTET
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