CORDIS Project
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This project aims to improve cardiac repair through cell therapy by enhancing the retention of cardiac cells and their beneficial factors. It involves developing a biodegradable biomaterial to support cell function and minimize complications.
Cell therapy has emerged as a promising therapeutic strategy for cardiac repair, showing modest cardiomyocyte protection and infarct size reduction.
It is under debate whether these outcomes are due to the implanted cells or their paracrine factors, as cells are scarce within a few weeks post-implantation.
Regardless, this is still not sufficient to promote cardiac remuscularization and reverse medium to severe myocardium injury and fibrosis.
Improved cell retention has been achieved with a subs…
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