CORDIS Project
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This project enhances Nuclear Magnetic Resonance (NMR) spectroscopy using Dynamic Nuclear Polarisation (DNP) to improve sensitivity and resolution for studying complex biological structures. It focuses on developing new sample formulations, advanced pulse sequences, and site-specific assignment methods, aiming to facil…
Dynamic nuclear polarisation (DNP) has recently emerged as a transformative technology to address the sensitivity limitation of Nuclear Magnetic Resonance (NMR) spectroscopy.
In the solid-state, hyperpolarisation has the potential to reveal unique insight into the structure of complex biological assemblies such as amyloid fibrils, membrane-embedded proteins, virus capsids or plant cell walls.
However, despite key pioneering studies, several challenges must be resolved before DNP Magic Angle Spin…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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