CORDIS Project
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This research investigates the immune response to HIV-2, a virus that does not typically lead to AIDS. By studying how dendritic cells recognize HIV-2, the project aims to uncover protective mechanisms that could inform new treatments for HIV-1.
Since its isolation in 1983 as a causative agent of AIDS, HIV-1 has remained an exceptional challenge.
The human immune system usually ultimately fails at controlling infection by the virus.
In contrast, most individuals infected with the related and poorly studied lentivirus HIV-2 do not develop AIDS.
The immune response is clearly implicated in this protection, but the mechanisms are not well understood. DCs are a unique type of immune cell that sense pathogens and couple this sensing to the a…
INSTITUT CURIE
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