CORDIS Project
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This project aims to develop a new animal model for studying HIV-1 infection using common marmosets. It focuses on understanding the host cell factors that restrict HIV-1 replication, which could aid in vaccine and therapy development.
Currently there are approximately 33.4 million people living with HIV-1 worldwide and it is estimated that every year AIDS claims about 2-3 million deaths while HIV-1 is responsible for an equal number of new infections.
In spite of the advances in the fight against HIV-1 since the isolation of the virus in 1983, there is still no vaccine available for the prevention of HIV-1 infection, and so far the available therapies have failed to eradicate the virus.
The use of animal models for the develo…
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