CORDIS Project
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This project investigates the roles of autophagy and lysosomal biogenesis in cell death caused by hypoxia and radiation in both normal and cancer cells. It aims to identify mechanisms that could enhance radiation sensitivity or protect normal cells during treatment.
The aims of the project are to investigate, for the first time, the mechanisms and the role of autophagy and lysosomal biogenesis in hypoxia and radiation-induced cell death in normal and cancer cells.
In project 1 we ask whether autophagy and lysosome biogenesis are involved in hypoxia and the acute and/or late toxicity of radiation in normal cells and tissues, and the eventual radioprotection that could be achieved by modifying process.
We will study the direct effects of ionizing radiation an…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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