CORDIS Project
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This project aims to uncover how the parasite Toxoplasma gondii alters host cell functions to enhance its survival. By identifying novel proteins secreted by the parasite, the research seeks to understand their impact on host immune responses and gene regulation.
Toxoplasma gondii is a widespread obligate intracellular protozoan parasite causing toxoplasmosis, a severe disease in immunocompromised or congenitally infected humans.
It can infect any type of nucleated cells and grow inside a parasitophorous vacuole (PV) from where it directs profound changes in their transcriptome, proteome and microRNome.
During invasion and creation of the PV membrane, apically oriented organelles called micronemes and rhoptries are discharged, followed later by release o…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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