CORDIS Project
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This project investigates meiotic recombination and its evolutionary significance. By studying the Prdm9 gene and its role in DNA double-strand breaks, it aims to enhance understanding of how recombination contributes to genetic diversity and reproductive success in various species.
During meiosis, homologous recombination plays a mechanical role by connecting homologous chromosomes, thus allowing proper chromosome segregation during the first meiotic division.
In most species, the absence of meiotic recombination leads to sterility.
In addition, recombination generates new combinations of alleles, increases genome diversity and plays a major role in genome evolution.Meiotic recombination is initiated by the programmed induction of DNA double-strand breaks (DSBs), but how t…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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