CORDIS Project
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The hRBP-virion project investigates the role of host RNA-binding proteins in Human Immunodeficiency Virus, aiming to develop new therapeutic strategies. By combining molecular biology and proteomics, it seeks to understand how these proteins affect the virus's lifecycle and resistance to treatment.
35 million people are currently infected with Human immunodeficiency virus (HIV), causative agent of AIDS.
While cocktails of anti-retrovirals can reduce viral loading to undetectable levels, drug resistance can emerge due to the high-mutation rate of the virus.
Moreover, no cure is yet achieved.
Therefore, it is crucial to explore complementary therapeutic strategies, a challenge that H2020 prioritizes in health.
The strict dependency of HIV on host RNA-binding proteins (RBPs) represents a pote…
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