CORDIS Project
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This project aims to understand the role of the chromosomal bouquet in meiosis, particularly how it influences spindle formation and chromosome dynamics. Using fission yeast, it explores the molecular mechanisms regulating these processes.
Organisms diversify and propagate their genomes throughout successive generations through the process of meiosis.
Understanding the process of meiosis is important, as defects in meiosis are a major cause of miscarriages in humans.
In meiotic prophase, telomeres gather near the microtubule organizing-center (MTOC) to form the so-called ‘bouquet’ structure.
The extraordinary conservation of the bouquet has suggested that it plays an important role in promoting successful meiosis.
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