CORDIS Project
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This project aims to enhance the understanding of how hematopoietic stem cells are formed during embryonic development. It seeks to identify the origins and processes involved in stem cell generation to improve transplantation therapies for blood disorders.
Hematopoietic Stem Cells (HSCs) are at the origin of all blood cells needed throughout life. HSC transplantation is used to treat patients with blood related disorders.
However, the number of HSCs available for clinic and research remains limited.
The production of large quantities of HSCs in vitro, for example by reprogramming or transdifferentiation of somatic cells to a HSC stage, would be a good solution, but this remains extremely difficult.
To overcome these problems, we must understand al…
KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW
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