CORDIS Project
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This project investigates how fat cells are maintained in humans, focusing on the differences between lean and obese individuals. By using a novel method to analyze cell turnover, it aims to understand the dynamics of adipose tissue, which is crucial for developing potential obesity treatments.
Owing to the increase in obesity, life expectancy may start to decrease in developed countries for the first time in recent history.
In humans the generation of fat cells (adipocytes) is a major factor behind the growth of adipose tissue during childhood.
The factors determining the fat mass in adults, however, are not fully understood.
Increased fat storage in fully differentiated adipocytes, resulting in enlarged fat cells, is well documented and thought to be the most important mechanism wher…
KAROLINSKA INSTITUTET
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