CORDIS Project
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This project investigates the role of Immunoglobulin E (IgE) in allergic diseases, aiming to identify predictive biomarkers for therapy response and explore mechanisms of IgE dependence. It also seeks to develop a vaccine approach for long-term allergy protection, enhancing understanding of allergic disease mechanisms…
IgE is a key driver of allergic diseases, which affect approximately one-third of the worlds population.
Monoclonal antibodies (mAbs) targeting IgE are approved for the treatment of allergic asthma, and show clinical benefit in a number of other allergic diseases.
Yet, a sizable portion of patients do not respond to the drug despite high levels of IgE.
There is a clear need to better define which allergy features depend (or not) on IgE, and to find predictive biomarkers in order to identify pati…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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