CORDIS Project
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This project investigates the immune response of memory B-cells to viral infections, focusing on HIV and Chikungunya virus. By generating specific antibodies from infected patients, it aims to enhance understanding of antiviral immunity and identify potential vaccine targets.
In addition to polyreactive “natural antibodies” that act as the first line of defense against invading pathogens, “humoral memory” is composed of high affinity antibodies that mediate long-lived immunity against infectious agents, e.g., providing protection against re-infection.
The molecular dissection of anti-pathogen B-cell responses using modern technologies to generate specific monoclonal antibodies allowed breakthrough discoveries on antiviral responses to Influenza and HIV.
The goal of t…
INSTITUT PASTEUR
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