CORDIS Project
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This project studies the interactions between Neisseria meningitidis and the human host to understand the mechanisms of bacterial colonization and the resulting vascular damage. It aims to identify potential therapeutic targets for meningococcal disease.
Neisseria meningitidis is still the major cause of bacterial meningitis and septicemia worldwide.
The septic shock caused by Neisserial invasive disease is characterized by the presence of skin lesions (petecchial rashes and purpura).
Despite the strong association of meningococcal disease and purpura as well as the serious prognosis associated with it, the bacterial factors and physiological processes underlying these events at molecular and cellular level are still largely undescribed.Here we…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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