CORDIS Project
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This project investigates how the hormone progesterone influences DNA methylation and hydroxymethylation in breast cancer cells. By analyzing these changes, the research aims to uncover the role of specific proteins in gene regulation, potentially leading to new diagnostic and therapeutic targets for hormone-dependent…
Hormone-dependent cancers affect millions of people worldwide and are a great burden to society, both financially and in terms of healthcare resources.
The steroid hormone progesterone plays critical roles in a variety of physiological functions as well as in the carcinogenesis of hormone-dependent cancers including breast and endometrial cancers.
Progesterone regulates gene expression through histone modifications and chromatin remodeling.
However, the role played by DNA methylation in this con…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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