CORDIS Project
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This project investigates the hygiene hypothesis, which suggests that infections may protect against allergic and autoimmune diseases. It combines epidemiological studies with experimental models to explore the relationship between infections and atopic conditions, aiming to identify protective mechanisms.
The hygiene hypothesis postulating the paradoxical protective role of infections on immune-mediateddiseases including atopy (i.e. atopic dermatitis, rhinitis, asthma) and more recently autoimmune diseases hasbeen the matter of extensive investigation.
The aim of the present project is to validate this hypothesisintegrating epidemiological and experimental studies.We will review in a meta-analysis published studies of direct and indirect markers of infections and atopicdiseases, and conduct a cas…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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