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The HyGlio project aims to develop a multifunctional system for the imaging and treatment of glioblastoma multiforme, a severe brain tumor. It combines various treatment strategies, including targeted drug delivery and real-time monitoring, to enhance therapeutic efficacy while minimizing side effects.
Glioblastoma multiforme (GBM) is the most frequent brain tumor in adults and is characterized by invariably fatal prognosis.
Although the incidence of GBM is less than 10 to 100,000, the median survival of approximate 1 year from diagnosis makes it a considerable socio-economic burden.
The presence of biological barriers for effective drug transport to the brain, the strong migrating-ability of the tumor and its rapid evolution into more aggressive and treatment-resistant variants, make GBM extr…
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