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The HyHeat project aims to enhance cancer treatment through hyperthermia by exploring the cellular responses to heat stress using gold nanoparticles. It seeks to identify genetic markers that could improve the efficacy of nanoparticle-mediated therapies.
Hyperthermia (HT) is currently used as a non-invasive technique for cancer therapy, whereby biological tissues are exposed to higher than normal temperatures, for selective ablation of tumoral cells.
However, the molecular mechanisms underlying the in vivo cellular responses to heat stress remain unclear to date.
The overall aim of the HyHeat project is to use an invertebrate model to screen the heating capabilities of different gold nanoparticles (AuNPs) in vivo, with the grand aim of understan…
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