CORDIS Project
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HyPlex aims to develop advanced polymeric nanoparticles for gene therapy, focusing on enhancing delivery efficacy through novel functionalization techniques. The project combines interdisciplinary research with practical training to support commercialization efforts in the field of gene therapy.
Gene therapy has long been seen as a promising solution to unmet clinical needs and the licencing of gene therapy SARS-CoV-2 vaccines has provided a flavour of the technology’s potential.
However, gene therapy still faces significant challenges in clinical and commercial translation including the need for effective and safe delivery vectors.
Polymeric nanoparticles offer great flexibility in gene vectors design, improved stability and easier scale-up of production compared to lipid nanoparticles…
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