CORDIS Project
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This project investigates how cells sense and adapt to low oxygen levels using the model organism Caenorhabditis elegans. It focuses on the role of specific microRNAs in hypoxic responses, aiming to uncover novel molecular mechanisms that could improve understanding of diseases related to oxygen deprivation.
Maintaining oxygen homeostasis is an essential requirement for all metazoa.
Oxygen is required for efficient generation of energy, however, as oxygen levels decrease (hypoxia), cells mount a variety of adaptive responses.
Each cell in the body can sense and respond to hypoxia, yet the molecular mechanisms that regulate these responses are only beginning to be delineated.
Hypoxia plays crucial roles in the pathophysiology of cancer, neurological dysfunction, myocardial infarction and lung disease…
KOBENHAVNS UNIVERSITET
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