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The HYPROTIN project focuses on studying the breast cancer susceptibility protein 1 (BRCA1) using advanced magnetic resonance techniques. It aims to provide insights into the protein's interactions and dynamics, which could inform drug design for hereditary breast and ovarian cancer.
HYPROTIN proposes a pioneering research platform for hyperpolarized magnetic resonance of breast-cancer related proteins that will revolutionize our view on tumorigenesis at the atomic level, through bottom-up reconstitution of medicinal relevant interaction pathways involving the breast cancer susceptibility protein 1 (BRCA1).
The risk to develop a hereditary breast or ovarian cancer (HBOC) increases to 55-65 % upon mutation of the BRCA1 gene.
Yet, little is known about the biochemistry of tumo…
UNIVERSITAT WIEN
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