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HypSurf seeks to enhance nuclear magnetic resonance (NMR) technology by improving its sensitivity and applicability. The project aims to make hyperpolarization methods accessible for a wider range of biomolecular studies, advancing research in structural biology and chemistry.
Across science, medicine, and industry, nuclear magnetic resonance (NMR) is a key technique with the unique capacity to provide atomistically detailed molecular models.
Its primary drawback, however, lies in its low sensitivity, limiting its ability to address critical scientific questions. A potential answer is hyperpolarization via dissolution dynamic nuclear polarization (dDNP), which can amplify NMR sensitivity 10,000-fold.
Despite this promise, dDNP remains a niche method constrained to a n…
UNIVERSITAT WIEN
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