CORDIS Project
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This project addresses retinal degenerative diseases by creating hybrid nanosynapses that restore lost synaptic connections in retinal cells. Utilizing plasmonic nanochannels to release neurotransmitters, it aims to mimic natural synaptic activity, paving the way for advanced retinal prosthetics.
Degenerative diseases of the retina, such as Retinitis pigmentosa (RP) and age-related macular degeneration (AMD), hit light-sensitive photoreceptors and leave bipolar cells (BCs) deprived of light-dependent synaptic input.
Neuronal degeneration starts affecting the presynaptic side of the synapse, while the denervated postsynaptic side preserves the ability to be activated.
This project targets the recovery of the lost synaptic light-mediated input to BCs by artificially reproducing two of the…
FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Netherlands, Eindhoven
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
INTITUTE OF MOLECULAR AND CLINICAL OPHTHALMOLOGY
Switzerland, BASEL
Type: Research institute
Activity type: Research Organisations
SME: No
France, Paris
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Germany, Tuebingen
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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