CORDIS Project
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The I-GENE project introduces a novel genome editing technology using nanotransducers to enhance safety and precision in gene editing. This method aims to enable targeted modifications in living cells, with applications in biotechnology and medicine.
CRISPR/Cas9 and enzyme-based editors hold promise for genome surgery by erasing harmful mutations and re-writing in helpful ones, but face critical barriers related to safety.
Here, we propose a new concept of genome engineering based on nanotransducers (NT), which aims to make safe previously impracticable applications of genome editing and transcriptional regulation by Cas9.
The methodology is based on laser-activation of a NT, which triggers a thermo-switchable double strand DNA break or clea…
UNIVERSITA DI PISA
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Poland, Sopot
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
Netherlands, Enschede
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
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