CORDIS Project
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The i-Thymus project aims to treat infants born without a thymus by using gene therapy to create thymus organoids from the patient's own cells. This innovative approach seeks to provide a minimally invasive solution to a life-threatening condition.
Each year, >250 babies are born without a thymus.
These babies have a life expectancy of 2-3 years.
The only cure is transplantation of thymus tissue, but this has a 30% mortality rate and costs almost >€2.5M.
We developed i-Thymus, a revolutionary cure based on the patient’s own cells leveraging innovative gene therapy to generate thymus organoids that can be implanted minimally invasively in the patient (Fig. 1).
We have already shown this works in functional proof of concept in vivo.
With thi…
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Netherlands, Leiden
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
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