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The ICARO project develops silicon-based microchips that carry pathogen antigens to enhance immune responses by improving antigen presentation to T cells. This innovative approach aims to create a new vaccination strategy that promotes long-lasting T cell responses against various intracellular pathogens and viruses.
Intracellular pathogens and viruses elicit immune responses by presenting their antigens to T cells.
At the same time, they have evolved immune evasion mechanisms which essentially reduce the antigenic repertoire that is presented to the immune system.
To overcome this problem, the EIC-funded ICARO project proposes to use silicon-based microchips that carry pathogen antigens and can be internalised by immune cells to aid antigen presentation.
These biochips are retained within cells for a long t…
ARRAYS-FOR-CELL NANODEVICES SL
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