CORDIS Project
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The project focuses on the dynamic behavior of microtubules, exploring how they can repair themselves and adapt their structure. By studying these mechanisms, the research aims to uncover new insights into microtubule function and its implications for cellular architecture.
Microtubules (MTs) are dynamic cytoskeleton filaments.
They permanently transit between growth and shrinkage.
This famous “dynamic instability” is governed by the addition and loss of tubulin dimers at their tips.
In contrast to the tip, the MT lattice was considered to be a passive structure supporting intracellular transport.
However, we recently found that MT lattice is dynamic and active!
Actually, tubulin dimers can be exchanged with the cytoplasmic pool along the entire length of the MT. T…
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