CORDIS Project
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The ICG68-PROG project focuses on developing molecular agents for real-time monitoring of c-Met expression in tumors. By creating gallium-68 binding tracers, it aims to enhance diagnosis and treatment monitoring of cancers where c-Met is overexpressed.
Aberrant hepatocyte growth factor/hepatocyte growth factor receptor (HGFR or c-Met) signalling is involved in the development of several tumor types.
Monitoring of c-Met expression in real time will assist in the diagnosis and in the monitoring of response to therapy.
The overall objective of the ICG68-PROG is to create a library of novel molecular agents able to effectively target c-Met and to efficiently bind gallium-68, and therefore to be exploited as c-Met PET imaging tracers.
The expected…
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