CORDIS Project
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This project investigates how intrinsically disordered proteins, which are flexible and adaptable, function as molecular chaperones to help cells respond to environmental stress. By combining biochemistry, protein design, and advanced mass spectrometry, it aims to uncover the role of protein plasticity in maintaining c…
One of the key issues in biology is determining the mechanisms underlying the response of organisms to changes in their environment.
It is known that ability of cells to sustain and recover after stress conditions depends on a well-developed and complex network of protein chaperones and co-chaperones.
This proposal addresses fundamental questions in a recently discovered subgroup of molecular chaperones, intrinsically disordered chaperones, which use plasticity for their ATP-independent chaperon…
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