CORDIS Project
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This research aims to uncover how gene regulatory elements, specifically enhancers, function in human cells. By using advanced genomic techniques, it seeks to characterize enhancer activity during key biological processes like hormone signaling and cell differentiation.
A major goal in biology is to understand how gene regulatory information is encoded by the human genome and how it defines different gene expression programs and cell types.
Enhancers are genomic elements that control transcription, yet despite their importance, only a minority of enhancers are known and functionally characterized.
In particular, their activity changes during cellular signalling or cell type transitions are largely elusive.
Furthermore, fundamental questions about transcriptiona…
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