CORDIS Project
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This project investigates the immune evasion strategies of Kaposi’s Sarcoma-associated herpesvirus by analyzing its proteome during infection. Using advanced proteomic techniques, it aims to uncover how the virus interacts with host cells, potentially identifying new targets for therapeutic interventions.
Kaposi’s Sarcoma-associated herpesvirus, or human herpesvirus 8, is an important cause of morbidity and mortality, causing tumors in immunosuppressed patients, in particular those with AIDS.
Like other herpesviruses, KSHV has evolved numerous mechanisms of escape from both the innate and adaptive host immune response.
These immune evasion strategies facilitate the virus’s oncogenic potential and contribute to its pathogenesis.
Beyond immune modulation, many viral proteins interact with component…
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