CORDIS Project
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This project aims to uncover the molecular mechanisms regulating the development and function of the vascular adventitia, the outer layer of blood vessels. It focuses on the transcription factor Tbx5 and its role in vascular organization, which may have implications for various diseases.
Vascular development and function are complex processes of utmost importance to the organism involving numerous steps and cell types.
One of the tissues participating in these processes is the vascular adventitia, the outermost layer of the vessel, mainly composed of connective tissue.
Recently, with the association of the adventitia to a growing number of diseases, its activities have become slowly uncovered and shown to participate in a number of developmental and homeostatic processes.
Despit…
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