CORDIS Project
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This project explores how early embryonic cells in mice decide to differentiate into specialized cell types or remain pluripotent. By identifying and manipulating specific genes, the research aims to understand the mechanisms behind these cell-fate decisions, which could inform future stem cell therapies.
Just prior to uterus implantation mammalian blastocyst stage embryos have already started the process of generating and segregating different cell types required for continued development.
Exactly how this remarkable transformation from a single fertilised egg to a highly ordered multi-cellular blastocyst occurs, within just a few days, remains a fascinating and enduring question.
During this time embryonic cells either start to adopt specialised functions (differentiate) or they can remain in a…
JIHOCESKA UNIVERZITA V CESKYCH BUDEJOVICICH
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