CORDIS Project
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The project investigates the role of interferon-beta in mitochondrial health and its implications for Parkinson's disease. By studying mitochondrial defects in specific mouse models, it aims to uncover new therapeutic targets for treating this neurodegenerative disorder.
Parkinson disease (PD) is the most common progressive neurodegenerative movement disorder.
Two prominent pathological features are associated with the neurological lesions: the appearance of cytoplasmic inclusion bodies called Lewy bodies, and defective mitochondria.
Despite recent progress in understanding the pathogenesis of PD, no curative treatments are available.
The host laboratory has very recently found a novel mechanism leading to PD: mice lacking interferon (IFN)-β (Ifnb–/–) or its rec…
KOBENHAVNS UNIVERSITET
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