CORDIS Project
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This project investigates how specific inputs from the thalamus influence the sensory map in the rodent brain's primary somatosensory cortex. By using advanced techniques to visualize and manipulate these connections, the research aims to understand how sensory deprivation affects cortical plasticity and input organiza…
The rodent primary somatosensory cortex (S1) contains a malleable topographic map, in which cortical columns functionally represent individual facial whiskers.
When all whiskers but two are trimmed, the cortical representations of the two spared whiskers partially fuse.
This fusion is associated and possibly facilitated by an increase in NMDAR-mediated dendritic nonlinearities (plateau potentials) in L2/3 neurons, which are dependent on inputs from the higher-order posteromedial thalamic complex…
UNIVERSITE DE GENEVE
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