CORDIS Project
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This project focuses on understanding the immune tumor microenvironment in melanoma to improve immunotherapy outcomes. By utilizing advanced imaging techniques, it aims to analyze cellular interactions and identify biomarkers that predict patient responses to treatment.
Immunotherapies targeting immune regulators are revolutionizing cancer treatment, most prominently in melanoma, but only for a subset of patients.
While it is known that the immune tumor microenvironment (iTME) plays a vital role in this process, there is limited understanding on how distinct tumor, immune and stroma cells interact as a system to collectively define progression and response to treatment, and there is no biomarker to predict patient response.
Tumors are spatially organized ecosys…
WEIZMANN INSTITUTE OF SCIENCE
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