CORDIS Project
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This project aims to develop a non-invasive technique to visualize and localize influenza virus nucleic acid replication, focusing on how the RIG-I receptor detects the virus in living cells. Understanding this interaction is crucial for enhancing the host's immune response against influenza infections.
Despite of intensive research the last decades, viral infection still represents a serious threat to human health.
One crucial aspect of the defence against viral infection is the activation of the host innate immune response.
Recent advances have highlighted the crucial role of the RIG-I receptor in triggering IFN synthesis upon virus infections.
This virus sensing pathway mediated by RIG-I is crucial for successful host defence against negative stranded RNA viruses infection such as influenza…
CANCER RESEARCH UK LBG
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