CORDIS Project
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This project explores how blood vessel formation is regulated during tissue development and repair. It focuses on the role of interstitial flow in growth factor signaling and aims to develop imaging tools to study vascular patterning in various physiological and pathological contexts.
Homeostasis of multicellular tissues relies on accurate match of vascular supply and drain to the needs of the tissue.
Multiple pathways are involved in detection, signalling and execution of the required steps involved in organization of blood and lymphatic vessels during embryonic development.
Similar mechanisms are utilized for overcoming changes in tissue requirements also in adult tissues and in pathological processes.
The goal of this work is to reveal the dynamic forces that shape the blo…
WEIZMANN INSTITUTE OF SCIENCE
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