CORDIS Project
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The project investigates how bacterial toxins are delivered into competitor cells using the type VI secretion system (T6SS). It aims to identify the mechanisms and domains that facilitate the transport of these toxins into the cytoplasm, enhancing our understanding of bacterial competition and aiding in the development…
Interbacterial competition is a key driver of the emergence of new bacterial strains. A widely used strategy during interbacterial competition is delivering toxins into competitors’ cytoplasm, where they target conserved components.
The type VI secretion system (T6SS), a machine that delivers toxic effectors into neighboring cells, is a major player in interbacterial competitions.
It fires an effector-loaded tube that penetrates the recipient cell envelope.
Although many T6SS effectors target th…
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