CORDIS Project
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This project investigates the role of sensory nerve cells in skin inflammation, particularly in allergic conditions like atopic dermatitis. By using mouse models and imaging techniques, it aims to uncover the interactions between immune cells and nerve cells, potentially identifying new therapeutic targets.
Preserving skin homeostasis depends on complex interactions among structural cells, immune cells, and the environment.
Dysregulation of this delicate equilibrium contributes to the development of type 2 immunity-associated skin inflammation (i.e., allergic skin inflammation), including atopic dermatitis (AD).
The skin is a complex organ harboring various tissue-resident immune cells (e.g., dendritic cells, mast cells and macrophages) and innervated by a meshwork of sensory nerves, including thos…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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