CORDIS Project
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This project investigates the genetic regulation of plasmacytoid dendritic cells to understand variations in antiviral responses and autoimmune diseases. By analyzing immune cells from diverse ancestry populations, it aims to identify novel immune subtypes and develop predictive models for precision medicine.
Antiviral immunity and autoimmune diseases exhibit high interindividual variability.
Despite intensive research, the genetic and molecular basis of this variability is incompletely understood. A key player of the immune system is the plasmacytoid dendritic cell(pDC).
Recent single-cell work revealed functionally distinct pDC subsets.
Considering that pDCs respond to many pathogens, this highlights a previously underappreciated functional diversity of pDCs.I hypothesize that the genetic regulatio…
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
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Germany, Munchen
Type: Public body
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
SME: No
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