CORDIS Project
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This project explores the innate immune system by investigating how danger signals activate immune responses and the regulatory mechanisms of NF-kB signaling. Using Drosophila as a model, it aims to identify new defense genes and understand the intricacies of immune regulation, which could inform therapeutic strategies…
The project seeks to advance our knowledge of the innate immune system at two different but complementary levels, sensing and regulation of signalling.
The first aim is centred on danger signals, and how they activate the immune system.
We propose to use high-throughput RNA sequencing, molecular biology, fly and bacterial genetics to investigate the global network of genes and pathways that are involved in either endogenous (DNA and chromatin components) or exogenous (pathogen virulence factors)…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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