CORDIS Project
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This project investigates the genetic diversity of immune receptors to understand why some individuals develop effective immune responses while others do not. It employs advanced sequencing techniques to analyze B and T cell receptor genes, aiming to uncover links between genetic variations and autoimmune diseases.
Why do vaccines protect some people but not all?
Why can some people develop potent neutralizing antibodies to infections, while others cannot?
Why do some people develop immune-associated diseases such as allergy, rheumatoid arthritis, multiple sclerosis and diabetes over their lifetimes, when the body has evolved to tolerate self?
The answer lies in the adaptive immune system. B and T lymphocytes of the adaptive system express highly polymorphic receptors that allow for the recognition of larg…
KAROLINSKA INSTITUTET
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