CORDIS Project
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This project seeks to identify biomarkers for Multiple Sclerosis by analyzing immune cell populations in monozygotic twins. Using advanced techniques like single-cell mass cytometry and machine learning, it aims to create clinically translatable biomarkers for monitoring disease activity and guiding therapy.
Multiple Sclerosis (MS) is a chronic inflammatory disease, where immune cell invasion into the central nervous system causes immunopathology and neurological deficit.
Although disease-modifying therapies dramatically reduce disease activity, they hold the potential for severe adverse effects while long-term disability prospects remain poor.
Moreover, there is to date no biomarker for monitoring the disease activity and to guide therapy decisions. I propose that the key to identifying such biomar…
UNIVERSITAT ZURICH
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