CORDIS Project
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This project aims to develop advanced magnetic resonance spectroscopy techniques to non-invasively assess changes in the intracellular environment associated with neurodegeneration. It focuses on understanding metabolite motion and its implications for cellular health.
Alterations of the intracellular space, including intracellular protein accumulation, organelle and cytoskeleton dislocation, and modifications in cell shape, are an early hallmark of many neurodegenerative processes.
The ability to assess and quantify these alterations non-invasively would be of tremendous interest, not only in a clinical context, but also for preclinical research.
However, no tool currently exists allowing such measurements.Diffusion-weighted magnetic resonance spectroscopy (D…
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