CORDIS Project
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This project aims to advance personalized treatment for heart failure by developing a clinically applicable test using patient-specific heart muscle cells derived from induced pluripotent stem cells. It focuses on assessing heart function and responses to drugs in engineered heart tissues to improve risk prediction and…
Heart failure (HF) is the common end-stage of different medical conditions.
It is the only growing cardiovascular disease and its prognosis remains worse than that of many malignancies.
The lack of evidence-based treatment for patients with diastolic HF (HFpEF) exemplifies that the current “one for all” therapy has to be advanced by an individualized approach.
Inherited cardiomyopathies can serve as paradigmatic examples of different HF pathogenesis.
Both gain- and loss-of-function mutations of…
UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF
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